Stress and fatigue from travel can make you sick. The good news is the body has immune system. But the condition of lack of sleep or poor dietary practices can cause the body susceptible to disease. The first thing to do when traveling, especially abroad is know what type of vaccine that is required before you leave. Type of vaccine needed depends on the condition of the destination country.
For example tourists from developed countries, it is recommended to get the typhoid vaccine, hepatitis A and B when visiting developing countries. If you want to visit Nepal or some parts of India, you are encouraged to get a meningitis vaccine in advance.
Or if you want to visit Southern America and Africa, you should get a yellow fever vaccine in advance. If the tropical regions of endemic malaria classified as Vanuatu, Papua, and so on, you have to take anti-malaria drugs.